11 research outputs found

    Unit Commitment Problem in Electrical Power System: A Literature Review

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    Unit commitment (UC) is a popular problem in electric power system that aims at minimizing the total cost of power generation in a specific period, by defining an adequate scheduling of the generating units. The UC solution must respect many operational constraints. In the past half century, there was several researches treated the UC problem. Many works have proposed new formulations to the UC problem, others have offered several methodologies and techniques to solve the problem. This paper gives a literature review of UC problem, its mathematical formulation, methods for solving it and Different approaches developed for addressing renewable energy effects and uncertainties

    Aedes Mosquito Surveillance Using Ovitraps, Sweep Nets, and Biogent Traps in the City of Yaoundé, Cameroon

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    Arbovirus diseases represent a significant public health problem in Cameroon and vector surveillance is a key component of prevention strategies. However, there is still not enough evidence of the efficacy of different sampling methods used to monitor Aedes mosquito population dynamic in different epidemiological settings. The present study provides data on the evaluation of ovitraps and different adult sampling methods in the city of Yaoundé and its close vicinity. Entomological surveys were carried out from February 2020 to March 2021 in two urban (Obili, Mvan), two peri-urban (Simbock, Ahala), and two rural (Lendom, Elig-essomballa) sites in the city of Yaoundé. The efficacy of three sampling methods, namely ovitraps, Biogent Sentinel trap, and sweep nets, was evaluated. Different ovitrap indices were used to assess the infestation levels across study sites; a general linear model was used to determine if there are statistical differences between positive ovitraps across ecological zones. A total of 16,264 Aedes mosquitoes were collected during entomological surveys. Ovitraps provided the highest mosquito abundance (15,323; 91.14%) and the highest species diversity. Of the five Aedes species collected, Aedes albopictus (59.74%) was the most commonly recorded in both urban and rural settings. Different Aedes species were collected in the same ovitrap. The ovitrap positivity index was high in all sites and varied from 58.3% in Obili in the urban area to 86.08% in Lendom in the rural area. The egg density index varied from 6.42 in Mvan (urban site) to 13.70 in Lendom (rural area). Adult sampling methods recorded mostly Aedes albopictus. The present study supports high infestation of Aedes species in the city of Yaoundé. Ovitraps were highly efficient in detecting Aedes distribution across study sites. The situation calls for regular surveillance and control of Aedes population to prevent sudden occurrence of outbreaks

    Bendiocarb and Malathion Resistance in Two Major Malaria Vector Populations in Cameroon Is Associated with High Frequency of the G119S Mutation (Ace-1) and Overexpression of Detoxification Genes

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    The spread of pyrethroid resistance in malaria vectors is a major threat affecting the performance of current control measures. However, there is still not enough information on the resistance profile of mosquitoes to carbamates and organophosphates which could be used as alternatives. The present study assessed the resistance profile of Anopheles gambiae s.l. to bendiocarb and malathion, at the phenotypic and molecular levels, in different eco-epidemiological settings in Cameroon. Anopheles gambiae s.l. mosquitoes were collected from four eco-epidemiological settings across the country and their susceptibility level to bendiocarb and malathion was determined using WHO tubes bioassays. The ace-1 target site G119S mutation was screened by PCR. Reverse Transcription quantitative PCR 3-plex TaqMan assays were used to quantify the level of expression of eight genes associated with metabolic resistance. Resistance to malathion and/or bendiocarb was recorded in all study sites except in mosquitoes collected in Kaélé and Njombé. The Ace-1 (G119S) mutation was detected in high frequencies (>40%) in Kékem and Santchou. Both An. gambiae and An. coluzzii were detected carrying this mutation. The cytochrome P450s gene Cyp6p3 associated with carbamate resistance and the glutathione S-transferase gene Gste2 associated with organophosphate resistance were found to be overexpressed. Genes associated with pyrethroid (Cyp6m2, Cyp9k1, Cyp6p3) and organochlorine (Gste2, Cyp6z1, Cyp6m2) and cuticle resistance (Cyp4g16) were also overexpressed. The rapid spread of resistance to organophosphates and carbamates could seriously compromise future control strategies based on IRS. It is therefore becoming important to assess the magnitude of bendiocarb and malathion resistance countrywide

    Knowledge, practices and perceptions of communities during a malaria larviciding randomized trial in the city of Yaoundé, Cameroon

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    Background Urban malaria is becoming a major public health concern in major cities in Cameroon. To improve malaria vector control, a pilot larviciding trial was conducted to assess its impact on mosquito density and malaria transmission intensity in YaoundĂ©. The present study investigated perceptions and practices of communities on malaria control during the larviciding trial implemented in YaoundĂ©. Methods Quantitative and qualitative data were collected in non-intervention and intervention areas. Quantitative data were collected during three cross-sectional surveys using a structured pre-tested questionnaire while qualitative data were obtained through interviews. A total of 26 in-depth interviews and eight focus group discussions with community members were performed. A binary logistic regression model was used to assess the perception of the community on larviciding impact on some malaria or bed nets use indicators. Results People living in intervention areas were 2.64 times more likely to know the mode of malaria transmission (95% CI: 1.82–3.84; p<0.001) and 1.3 time more likely to know mosquito breeding habitats (95% CI: 1.06–1.56; p = 0.009) compared to those living in non-intervention areas. In intervention areas, interviewee opinions on larviciding were generally good i.e. most interviewees reported having noticed a reduction in mosquito nuisance and malaria cases following larviciding implementation; whereas in non-intervention areas no report of reduction of mosquito nuisance was recorded. LLINs were regularly used by the population despite the implementation of larviciding treatments. There was high interest in larviciding program and demand for continuation, even if this needs the community involvement. Conclusion The larviciding program in the city of YaoundĂ© did not negatively affected community members’ behaviour and practices concerning the use of treated nets. The study indicated the acceptance of larviciding program by the population. This positive environment could favour the implementation of future antilarval control activities in the city of YaoundĂ©

    The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance

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    INTRODUCTION Investment in Africa over the past year with regard to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing has led to a massive increase in the number of sequences, which, to date, exceeds 100,000 sequences generated to track the pandemic on the continent. These sequences have profoundly affected how public health officials in Africa have navigated the COVID-19 pandemic. RATIONALE We demonstrate how the first 100,000 SARS-CoV-2 sequences from Africa have helped monitor the epidemic on the continent, how genomic surveillance expanded over the course of the pandemic, and how we adapted our sequencing methods to deal with an evolving virus. Finally, we also examine how viral lineages have spread across the continent in a phylogeographic framework to gain insights into the underlying temporal and spatial transmission dynamics for several variants of concern (VOCs). RESULTS Our results indicate that the number of countries in Africa that can sequence the virus within their own borders is growing and that this is coupled with a shorter turnaround time from the time of sampling to sequence submission. Ongoing evolution necessitated the continual updating of primer sets, and, as a result, eight primer sets were designed in tandem with viral evolution and used to ensure effective sequencing of the virus. The pandemic unfolded through multiple waves of infection that were each driven by distinct genetic lineages, with B.1-like ancestral strains associated with the first pandemic wave of infections in 2020. Successive waves on the continent were fueled by different VOCs, with Alpha and Beta cocirculating in distinct spatial patterns during the second wave and Delta and Omicron affecting the whole continent during the third and fourth waves, respectively. Phylogeographic reconstruction points toward distinct differences in viral importation and exportation patterns associated with the Alpha, Beta, Delta, and Omicron variants and subvariants, when considering both Africa versus the rest of the world and viral dissemination within the continent. Our epidemiological and phylogenetic inferences therefore underscore the heterogeneous nature of the pandemic on the continent and highlight key insights and challenges, for instance, recognizing the limitations of low testing proportions. We also highlight the early warning capacity that genomic surveillance in Africa has had for the rest of the world with the detection of new lineages and variants, the most recent being the characterization of various Omicron subvariants. CONCLUSION Sustained investment for diagnostics and genomic surveillance in Africa is needed as the virus continues to evolve. This is important not only to help combat SARS-CoV-2 on the continent but also because it can be used as a platform to help address the many emerging and reemerging infectious disease threats in Africa. In particular, capacity building for local sequencing within countries or within the continent should be prioritized because this is generally associated with shorter turnaround times, providing the most benefit to local public health authorities tasked with pandemic response and mitigation and allowing for the fastest reaction to localized outbreaks. These investments are crucial for pandemic preparedness and response and will serve the health of the continent well into the 21st century

    Nouvelle approche d'Ă©valuation de potentiels de ressources bioclimatiques en climat chaud et humide

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    International audienceSpĂ©cificitĂ© d'une Ă©tude en climat chaud Base de la mĂ©thodologie Conclusion Application et synthĂšse des rĂ©sultats Perspectives 40% 10% 25% 16% 9% Consommation d'Ă©lectricitĂ© par usage – Djibouti, 2013 Climatisation Eclairage Brasseur d'air Regrigerateur Autre Electromenagers 2 3 4 5 6 Cette Ă©tude propose une nouvelle dĂ©finition de potentiels d'utilisation de ressources bioclimatiques adaptĂ©e au climat chaud et humide et permettant le rafraichissement des bĂątiments. Dans le contexte du climat chaud, le principal dĂ©fi Ă  relever est celui de la climatisation. A ce dĂ©fi s'ajoutent deux problĂšmes majeurs: L'inadaptation des techniques de construction, Le manque des travaux sur les ressources Ă©nergĂ©tiques disponibles, 5 10 15 20 25 30 35 40 0 30 60 90 120 150 180 210 240 270 300 330 360 TempĂ©rature de l'air [°C] TempĂ©rature du ciel [°C] Jours TempĂ©rature [°C] 30 32 34 36 38 40 42 44 0 40 80 120 160 200 240 280 320 360 T sol (0,t) T sol (0.5,t) T sol (2,t) T sol (3,t) T sol (4,t) TempĂ©rature du sol [°C

    West Africa Pearl Millet data set

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    Research was conducted in Burkina Faso, Mali and Niger for the Sahel and Sudan Savanna agroecological zones. Trials had similar basic treatment structures for determination of response functions for N, P, and K, and a diagnostic treatment for resposne to Mg, S, Zn and B. Most treatments in Niger were intercroped with cowpea and with 2.5 Mg ha-1 yr-1 manure applied but had additional treatments for determination of the effect of manure and/or intercropping on yield and response. Most treatments in Mali were sole crop pearl millet with added treatments determination of the effect of intercropping on yield and response, all with no manure applied. In Burkina Faso, trials were conducted at Dori in 2014-2015 and all treatments were with pearl millet sole crop with or without 5 Mg ha-1 manure applied in 2014 and evaluating the residual effect of manure in 2015

    IRIT at e-Risk

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    International audienceIn this paper, we present the method we developed when participating to the e-Risk pilot task. We use machine learning in order to solve the problem of early detection of depressive users in social media relying on various features that we detail in this paper. We submitted 4 models which differences are also detailed in this paper. Best results were obtained when using a combination of lexical and statistical features

    Pyrethroid Resistance Situation across Different Eco-Epidemiological Settings in Cameroon

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    Rapid emergence and spread of pyrethroid resistance in Anopheles gambiae populations is among the main factors affecting malaria vector control in Cameroon, but there is still not enough data on the exact pyrethroid resistance status across Cameroon. The present study assessed pyrethroid resistance profile in different eco-epidemiological settings in Cameroon. Susceptibility bioassay tests were performed with F0 An. gambiae females aged three to five days. Mosquito susceptibility to both permethrin and deltamethrin was assessed. Species of the An. gambiae s.l. complex were identified using molecular diagnostic tools. Target site mutations conferring resistance were detected using Taqman assays. Quantitative reverse transcription-real-time PCR (qRT-PCR) 3-plex TaqMan&reg; assays were used for the quantification of detoxification genes implicated in pyrethroid resistance. An. gambiae, An. coluzzii and An. arabiensis were identified in the different settings. An. gambiae was dominant in Santchou, K&eacute;kem, B&eacute;labo, Bertoua and Njomb&eacute;, while An. coluzzii was abundant in Tibati and Ka&eacute;l&eacute;. High frequencies of the kdr L1014F allele ranging from 43% to 100% were recorded in almost all sites. The L1014S kdr allele was detected at low frequency (4.10&ndash;10%) only in mosquito populations from Njomb&eacute; and Tibati. The N1575Y mutation was recorded in Ka&eacute;l&eacute;, Santchou, Tibati and Bertoua with a frequency varying from 2.10% to 11.70%. Six Cytochrome P450 genes (Cyp6p3, Cyp6m2, Cyp9k1, Cyp6p4, Cyp6z1, and Cyp4g16) were found to be overexpressed in at least one population. Analysis of cuticular hydrocarbon lipids indicated a significant increase in CHC content in mosquito populations from Ka&eacute;l&eacute; and Njomb&eacute; compared to K&eacute;kem, B&eacute;labo and Bertoua populations. The study indicated high pyrethroid resistance across different ecological settings in Cameroon with different profile of resistance across the country. The present situation calls for further actions in order to mitigate the impact of insecticide resistance on vector control measures
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